Race is a risk factor for calcinosis in patients with JDM – early results from the CARRAnet registry study
نویسندگان
چکیده
Purpose Previously established risk factors for calcinosis include duration of disease and the length of time to treatment, suggesting early aggressive treatment may be important in preventing calcinosis. Race has also been suggested to be a risk factor, but this observation was thought to be secondary to delays in treatment. We utilized the CARRAnet registry to investigate potential risk factors for calcinosis.
منابع مشابه
Diagnostic evaluation and medication usage in a cohort of subjects with juvenile dermatomyositis from the CARRAnet registry
Purpose Juvenile dermatomyositis (JDM) is a rare disease which has been difficult to evaluate objectively due to the low incidence of disease. The Childhood Arthritis and Rheumatology Research Alliance (CARRA) initiated a multicenter observational registry to create a clinical database for the major rheumatic diseases of childhood, including JDM. Initial data from the JDM cohort (prevalent and ...
متن کاملClinical characteristics of children with juvenile dermatomyositis recruited within the first 7 months of the CARRAnet registry
Purpose Performing quality clinical and translational research in juvenile dermatomyositis (JDM) is difficult due to the rarity of the disease. The Childhood Arthritis and Rheumatology Research Alliance (CARRA) initiated a multicenter observational cohort study to create a foundational clinical database for the major rheumatic diseases of childhood, including JDM. Initial data from the JDM coho...
متن کاملCharacteristics and outcome of children with juvenile dermatomyositis in Cape Town: a cross-sectional study
BACKGROUND Juvenile dermatomyositis (JDM) is a rare idiopathic inflammatory childhood myopathy of uncertain aetiology. The demographic and clinical presentation of JDM may differ by race and geographic regions. Few studies have described the characteristics of JDM patients from Africa. METHODS We conducted a retrospective observational study to determine clinical characteristics and outcomes ...
متن کاملAge-dependent inhibition of ectopic calcification: a possible role for fetuin-A and osteopontin in patients with juvenile dermatomyositis with calcinosis.
OBJECTIVES To assess if age and/or age-dependent variations in the levels of two major calcification regulatory proteins, fetuin-A and osteopontin, could be associated with an increased risk of calcinosis in children with juvenile dermatomyositis (JDM). METHODS The frequency of calcinosis was derived from a national UK database of 212 cases of JDM. Serum fetuin-A and plasma osteopontin levels...
متن کاملAn Epidemiologic Study on Basal Cell Carcinoma and its Related Risk Factors in Patients Referred to Razi Hospital Tumor Clinic in Autumn 2005-2006
Background: Basal cell carcinoma (BCC) is the most common cutaneous malignancy. UV light is an important risk factor for BCC, as well as X-ray and other ionizing radiations. The aim of this study was evaluation and risk factor assessment of BCC cases referred to Razi hospital tumor clinic. Methods: Patients referred from general clinics with skin biopsies consistent with Basal Cell Carcinoma we...
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عنوان ژورنال:
دوره 10 شماره
صفحات -
تاریخ انتشار 2012